Biomolecular Sensing: Bridging Biology and Engineering

Biomolecular sensing, often referred to as biosensing represents a dynamic field where biology and engineering converge to create innovative solutions for the detection of biological molecules with high specificity and sensitivity. By bridging the gap between biological systems and engineered devices, biomolecular sensing continues to revolutionize our ability to understand and interact with the molecular world. 

This seminar will discuss some of the fundamental principles underlying biomolecular sensing, including molecular recognition, signal transduction, and amplification mechanisms. It will explore key detection techniques such as optical, electrochemical, and nanomaterial-based sensing. Furthermore, the talk will focus on the development of a lab-on-chip device for the detection of microRNAs (miRNAs)—a crucial cancer biomarker circulating in the bloodstream. Specific technologies, including an Au-based microelectrofluidic device, a single-crystal Ga₂O₃ sensor, and a U-bent fiber optic sensor, will be highlighted.